This is a framed art print of the painting The Sampler by British artist Leonard Campbell Taylor. The scene depicts two women in an interior setting, one of whom appears to be working on a piece of embroidery (a sampler). The print in the image was likely published around 1933.
Label on back shows Wunderly Bros Fine Art in Pittsburg Pennsylvania. A print of The Sampler framed by a notable dealer like Wunderly Bros. can be more desirable than a generic framing.